Other factors, including gender, tumor extending to adjacent organ/tissue in UNKTL, regional lymph node involvement, bony invasion or perforation, ESR >30 mm/hr, β2- microglobulin, hemoglobin<110 g/L and pegaspargase replacement of L-asparaginase had no significant effects on OS or PFS (Table 3). Here, ASPG is linked to neoplasm.