The associated variant tagged a total of 6 SNPs of which 3 were located in intergenic region and the other three in intron 1 of CDKN2A, 3’UTR of CDKN2B and intron 3 of ANRIL. Association with melanoma risk was also observed for the variant T-allele of rs2811710 located in intron 1 of CDKN2A/ARF. The gene discussed is CDKN2A; the disease is melanoma.