In the present study, when we carried out pathway analysis using three platforms, we found several immune-related pathways showing significant differences between the ASD patients and controls, including the RIG-I-like receptor signaling, the toll-like receptor signaling, the allograft rejection, the primary immunodeficiency, the cytokine-cytokine receptor interaction, the chemokine signaling, the intestinal immune network for IgA production, and the Jak-STAT signaling pathways. This evidence concerns the gene SOAT1 and inborn error of immunity.