Among the IPF patients, the serum levels of IL-6 [median 4.03 pg/ml (range 0.00 – 32.35 pg/ml), p < 0.0001] and IL-10 [median 3.56 pg/ml (range 0.00 – 12.17 pg/ml), p < 0.0001] were significantly higher than those in the healthy controls [median 0.00 pg/ml (range 0.00 – 267.38 pg/ml) for IL-6 and median 0.8 pg/ml (range 0.00 – 7.56 pg/ml for IL-10)]. This evidence concerns the gene IL10 and idiopathic pulmonary fibrosis.