This final list includes six genes associated with ALT elevation and/or hepatic steatosis (MAPK10, CPN1, TRIB1, PNPLA3, SAMM50 and MICAL3) (Chambers et al., 2011; Sookoian and Pirola, 2011; Yuan et al., 2008). This evidence concerns the gene PNPLA3 and fatty liver disease.