In humans, reported alcohol intake is positively associated with total IgE cross-sectionally, although associations with allergen-specific sensitization have been inconsistent.8, 9, 10 Studies from Denmark have found that reported alcohol consumption in pregnancy was positively associated with total IgE in cord blood11 and postnatal atopic dermatitis12, 13 but not with hospitalization for asthma in childhood.14 This evidence concerns the gene IGHE and asthma.