IL10 and type 2 diabetes mellitus: In the present study, a meta-analysis was performed to examine the association between three IL-10 polymorphisms and T2DM risk, by critically reviewing 8 studies on IL-10 −592C/A polymorphism (2,729 patients and 2,620 controls), 4 studies on IL-10 −819C/T polymorphism (1,365 patients and 987 controls), and 6 studies on IL-10 −1082A/G polymorphism (1,835 patients and 2,257 controls).