Significant differences were found between non-NASH and NASH groups in age (P<0.01), AST (P<0.01), IRI (P<0.05), ferritin (P<0.05), platelet count (P<0.01), hyaluronic acid (P<0.01), FIB-4 index (P<0.01), Fuc-Hpt (P<0.01), and M30 antigen (P<0.05). This evidence concerns the gene MRS2 and metabolic dysfunction-associated steatohepatitis.