Univariate analysis revealed that age >47 years old, tumor size >3 cm, alpha-fetoprotein >8 ng/mL, albumin ≤4 g/dL, AST >42 U/L, ALT >50 U/L, AST/ALT >0.89, presence of occult HBVCI, and absence of overt HBVCI were associated with a shorter disease-free survival. This evidence concerns the gene ALB and neoplasm.