After adjusted for other confounding factors (Table 3), multivariate analysis revealed that tumor size >3 cm (P = 0.007), alpha-fetoprotein >8 ng/mL (P = 0.013), albumin ≤4 g/dL (P = 0.003), ALT >50 U/L (P = 0.022), presence of occult HBVCI (P = 0.027), and absence of overt HBVCI (P = 0.015) associated with a shorter disease-free survival. Here, AFP is linked to neoplasm.