According to the definition initially described by Lok et al. (5) and subsequently modified by Yeo et al. (10), hepatitis was defined as more than three times increase in alanine aminotransferase (ALT) that exceeded the upper limit of normal range (ULN) or an absolute increase of ALT which is more than 100 U/L compared to baseline pre-chemotherapy value. Here, GPT is linked to hepatitis A virus infection.