Epigenetic mediation of gene-environment interactions in PTSD has also been reported for other genes related to synaptic function, such as genes coding for Neuropeptide Y (NPY), BDNF, and molecules involved in the noradrenergic and dopaminergic systems (Boulle et al., 2012; Russo et al., 2012; Skelton et al., 2012; Wu et al., 2013). The gene discussed is NPY; the disease is post-traumatic stress disorder.