Three further case reports described a further three RyR2 mutations all of which showed AT and/or AF in addition to CPVT without abnormalities in cardiac structure (Sumitomo et al., 2007; Pizzale et al., 2008; Kazemian et al., 2011). This evidence concerns the gene RYR2 and catecholaminergic polymorphic ventricular tachycardia.