A more recent study has demonstrated that loxapine treatment downregulates both D2-like and 5HT-2A in platelets from patients with schizophrenia (Nord and Farde, 2011), with the latter finding being contradictory to that by Pandey et al. Further evidence indicating that platelets of patients with schizophrenia may provide a suitable tissue for a source of biomarker discovery has come from another recent study demonstrating that platelets derived from patients with schizophrenia demonstrated hypoglutamatergic release of Ca2+ (Miyake et al., 2011). The gene discussed is HTR2A; the disease is schizophrenia.