In the ALCs, the SOD2 mRNA copies/μg of total RNA was about ninefold higher in the patients with PEX and cataract (median=23,288 mRNA copies/μg of total RNA) compared to the control cataract group (median=2,600 mRNA copies/μg of total RNA), and statistical significance was found (p=0.0015, Mann–Whitney U test; Figure 1A). The gene discussed is SOD2; the disease is cataract.