TCF7L2 and type 2 diabetes mellitus: When we compared D+Co vs 100+, D+macroCo vs 100+ and D+microCo vs 100+, the TCF7L2 rs7903146 resulted associated with T2D complicated patients with an OR = 1.89 (95% CI 1.43-2.50, p_value = 5.473*10−6), 2.18 (95% CI 1.45 -3.29, p value = 1.538*10−4) and 1.84 (95% CI 1.31 - 2.58, p_value = 2.68*10−4), respectively (Table 1).