To determine the correlation between the kinetic patterns of DNA damage and repair, as assessed using the γ-H2AX-specific fluorescence with the in vitro assay, and OM, the relative fluorescence of γ-H2AX was estimated in 15 patients with mild OM and 10 patients with severe OM at different time points during radiotherapy (Figure 4). The gene discussed is H2AX; the disease is ocular melanoma.