HNF4A and diabetes mellitus: Other studies have identified high-sensitivityC-reactive protein (hsCRP), a known HNF1A target gene [26,27] to be reduced in serum levels of subjects with HNF1A-MODY, compared to other forms of diabetes such as type 1 diabetes, type 2 diabetes, HNF4A-MODY, and glucokinase-MODY [28-30].