ENO2 and autism: While a comparison of homer 1/NSE values between adults with autism who took anticonvulsants (mean of 0.13 ± 0.086) versus those who did not (mean of 0.23 ± 0.085) did not show a significant difference (P <0.063), it is possible that the reduction of homer 1/NSE is at least partly due to anticonvulsant use.