COL1A2 and triple-A syndrome: So far some extracellular matrices such as aminoterminal propeptide of type III procollagen (PIIINP) and carboxyterminal propeptide of type I procollagen (PICP), thrombus-associated proteins such as fibrinogen, D-dimer and tissue plasminogen activator (tPA) and matrix-degrading enzymes such as matrix metalloproteinase-9 (MMP-9) have been reported as potential circulating biomarkers for AAA diagnosis in case–control study [4].