Schoffelen et al. (2010b) developed procedures for radiolabeling a small hapten-peptide (1451 Da) with 68Ga or 18F to compare their specificity with 18F-FDG for detecting tumors using a pretargeting procedure in animal models of CEA-positive-human colonic tumor and a CEA-negative tumor, or a local inflammation. The gene discussed is CEACAM5; the disease is colonic neoplasm.