Circulating miRNAs have also been found to be linked to various PC risk scores such as tumor stage, CAPRA (Cancer of the Prostate Risk Assessment) and D'Amico scores (miR-20a, miR-21, miR-145, and miR-221) (Shen et al., 2012) or have predictive abilities similar to that of circulating tumour cell (CTC) counts, PSA, and lactate dehydrogenase (LDH) levels of PC patients (miR-21, miR-141) (Gonzales et al., 2011). This evidence concerns the gene KLK3 and neoplasm.