SRC and melanoma: However, in Drosophila neurons (Bogdan and Klambt, 2003) and cultured human melanoma cells (Steffen et al., 2004), there are large pools of W/SRC with a perinuclear and organelle-like punctate localization that have no obvious relationship to cell shape or motility, raising uncertainty about the cellular mechanisms of W/SRC activation and the importance of different organelle systems.