CD163 and systemic sclerosis: The mean concentration of sCD163 in patients with SSc (mean ± SD 984 ± 420 ng/mL, range 302 to 2,275 ng/mL) was significantly higher than in HC (823 ± 331 ng/mL, range 329 to 1,659 ng/mL; P = 0.023) (Figure 1).