Over the past few years, mutations in genes encoding sarcomere proteins, the beta-myosin heavy chain (MYH7), alpha-cardiac actin (ACTC1), cardiac troponin T (TNNT2), cardiac myosin- binding protein C (MYBPC3), alpha-tropomyosin (TMP1) and cardiac troponin I (TNNI3) have been identified in a significant proportion of patients with LVNC [14-16]. Here, TNNI3 is linked to left ventricular noncompaction.