Immunohistochemical staining showed that the tumor cells including area of adenomatous hyperplasia were diffusely positive for EMA, CK, and CK7, focally positive for CEA and Vimentin, negative for CK 5/6, CD30 , AFP, HCG-β, TTF-1, PSA, CA19-9, CA125, Calretinin, PLAP, CD117 and α-inhibin. The gene discussed is CEACAM5; the disease is neoplasm.