Decreased CSTP1 staning was detected in all the pTa and pT1 tumor tissues compared to adjacent non-cancerous tissues, while only 10 of the 26 cases of muscle invasive bladder cancer tissues shown a decreased staining of CSTP1, no change was observed in 11 of the muscle invasive bladder cancer tissues, and the remaining 5 showed an increased staining of CSTP1, the representatives of CSTP1 staining in pTa and pT1 bladder cancer tissues were presented in Fig. 8A. The gene discussed is CSTP1; the disease is neoplasm.