The first cluster (pink), composed of SOD2, CCL3, CCL2, IL1, CCL4 and IL10, was more repressed in leprosy patients than the second cluster (yellow), composed of mitochondrial genes, IL12 and Bad, while the third cluster (blue) included only genes up-regulated in leprosy patients (E3-ligase gene and LDLR). The gene discussed is CCL4; the disease is leprosy.