TARDBP and frontotemporal dementia: The neuropathology of FTD can include the presence of degenerating neurons containing intracellular inclusions positive for either the microtubule-associated protein Tau (MAPT), TAR DNA-binding protein (TDP-43), a highly conserved heteronuclear ribonuclearprotein (hnRNP) or other ubiquitylated proteins (reviewed in Mackenzie et al., 2010).