Moreover, to aid in the interpretation of our data, we further restricted our FTD subgroups to those whose clinical symptoms are highly correlated with specific neuropathological subgroups: FTD-MND (n=12, probable TDP-43 neuropathology), CBS (n=10, probable Tau pathology), PSPS (n=7, probable Tau pathology) and PNFA (n=10, probable Tau pathology). The gene discussed is TARDBP; the disease is frontotemporal dementia.