Here we have shown the presence of survivin specific T cells in PBMC of an HNSCC patient by means of tetramer staining (Figure 1A; binding of survivin(5–14): TLPPAWQPF) and in the draining lymph node of a patient with advanced breast cancer by means of ELIspot (Figure 1B; recognition of native survivin95-104: ELTLGEFLKL). The gene discussed is BIRC5; the disease is head and neck squamous cell carcinoma.