The proportion of patients with low Annexin A1 expression was higher amongst patients with moderate/poorly differentiated tumor (Figure 1) (78/167) and positive alcohol use (44/88) compared to those with well differentiated tumor (Figure 1) (18/65) and negative alcohol use (52/144), respectively There was no significant difference between pathologic differentiation grade and alcohol use (P=0.499). The gene discussed is ANXA1; the disease is neoplasm.