Some drugs that have already received regulatory approval (e.g., the anti-vascular endothelial growth factor antibody bevacizumab) (Hurwitz et al., 2004) exert antitumor effects at least in part by normalizing the tumor vasculature and enhancing tumor accumulation of chemotherapeutic drugs (Willett et al., 2004). This evidence concerns the gene VEGFA and neoplasm.