During EMT of prostate cancer cells, the expression of transcription factors such as Snail, Slug, Twist, E47, ZEB1, and ZEB2 is increased, which leads to increased expression of N-cadherin and vimentin and concomitantly decreased expression of E-cadherin and cytokeratins [42]–[45]. Here, TWIST1 is linked to Familial prostate cancer.