SOST and type 2 diabetes mellitus: In contrast, Jastrzebski et al. (2013) did not confirm the correlation between bone formation and serum sclerostin; however, such study was performed in mice that, in addition, were not diabetic, therefore in a quite different setting compared to the previous two studies (Gaudio et al., 2012; Gennari et al., 2012) that were conducted in T2DM patients.