SeV infection led to a significant increase of the virus-induced representative proteins IFIT1 (ISG56), IFIT2 (ISG54) and DDX58 (RIG-I) at 16 hours post-infection with knockdown of WNT2B or WNT9B by two independent shRNAs (Figure 2B and Figure S3 for knockdown efficiency). The gene discussed is WNT2B; the disease is infection.