However, tumours in IL-4Rα−/− mice were significantly smaller than tumours from WT mice [mean (standard deviation, SD) maximum tumour diameter 2.3 (1.0) mm in IL-4Rα−/− mice versus 3.7 (1.3) mm in WT mice; P = 0.05; Mann–Whitney U-test; Figure 2B]. Here, IL4R is linked to neoplasm.