Compared with high‐dose AngII, low‐dose AngII treatment in S3KO mice reduced aortic expansion (P<0.001) and aneurysm severity (P<0.01) and improved the survival rate (P=0.0376), but it did not significantly decrease the incidence of aneurysms (Figures 1D, 2F through 2H). This evidence concerns the gene AGT and aneurysm.