CD44 and neoplasm: CD44+, MYD88+ cells from ascites and solid tumors have been characterized by constitutive nuclear factor kappa beta (NF-κβ) activity, cytokine and chemokine production, high capacity for repair, chemoresistance to conventional chemotherapies, resistance to TNF-α-mediated apoptosis, capacity to form spheroids in suspension, and the ability to recapitulate in vivo the original tumor [8].