In addition, poor differentiation, tumor size > 3 cm, TNM stage III or IV, lymph node metastases, adjacent tissue invasion, no resection, and positive expression of CCT2 and/or PDIA3 were all negatively correlated with post-surgery survival rate, and positively correlated with patient mortality rate (Table 7, P < 0.05). The gene discussed is PDIA3; the disease is neoplasm.