CCNA1 and cervical intraepithelial neoplasia: Methylation of the promoters CCNA1 and C13ORF18 in cervical scrapings is found to be strongly associated (P < 0.0005) with CIN2 (moderate cervical intraepithelial dysplasia) and higher grade stages of cervical dysplasia, as was determined in the study by Yang et al. [63].