In 2005 a novel set of fusion genes were described in nearly half of the PCa cases [4] involving the 5′-untranslated region of TMPRSS2 (21q22) and the codifying region of some transcription factors such as ERG (21q22), ETV1 (7p21), and ETV4 (17q21) among others [5]. The gene discussed is TMPRSS2; the disease is posterior cortical atrophy.