Ghrelin-induced hyperglycemia: 5.9±0.2 mmol/l (ghrelin) vs 5.4±0.1 mmol/l (saline), P=0.009, in the basal period and insulin resistance during the clamp period, where ghrelin concentrations significantly reduced the glucose infusion rate (M value; mg/kg per min): 1.40±0.47 (ghrelin) vs 3.19±0.58 (saline), P<0.001. The gene discussed is GHRL; the disease is Hyperglycemia.