Subjects with higher PTH levels were significantly older, had more often type 2 diabetes, were more often hypertensive, had higher BMI, larger waist circumference, higher blood pressure (SBP and DBP), higher fasting blood glucose, higher post-load glucose, lower HDL cholesterol, lower 25(OH)D levels, and higher BNP levels with significant trends across the PTH quartiles (Table 1). The gene discussed is PTH; the disease is type 2 diabetes mellitus.