Positive cytology and adhesions were, in many studies, strongly connected with the tumour’s metastatic potential, and with a particular molecular arrangement, in particular loss of e-cadherin [39], positive of mib-1 and p-53 [33], aneuploidy of DNA [34, 35, 36] and mitotic activity index (MAI) [37]. Here, CDH1 is linked to neoplasm.