Moreover, more than 20 common genetic variants have been shown to contribute to breast cancer risk; among these, the fibroblast growth factor receptor 2 (FGFR2) polymorphism rs2981582 as well as loci close to the cell cycle regulator Cyclin D1 (CCND1) at 11q13 are the most prominent risk loci (Easton et al., 2007; Lambrechts et al., 2012). This evidence concerns the gene CCND1 and breast cancer.