Surprisingly, even though targets such as the serotonin 1A (5-HT1A) receptor, serotonin 2 (5-HT2) receptor, the serotonin transporter (5-HTT), and the gamma-aminobutyric acid-A (GABAA) receptor have yielded drugs with known efficacy, the relation between the genetic background of these targets and anxiety symptoms and disorders is little understood. Here, SLC6A4 is linked to Anxiety.