IL1B and diabetes mellitus: In research done on 85 patients with diabetes and 23 healthy subjects, although serum NO and IL-1β had a synergic effect on the development of diabetes, no difference in the serum levels among the groups was observed; and as a result of this, no assessment can be carried out about the functions of these parameters in diabetic patients just by taking the levels of serum NO and IL-1β into consideration (Yenisey et al. 2001).