The strains from patient 1 and patient 2 were identical according to both szP sequencing and MLST, which supports the close relationship between the Hum1 and Hum2 isolates, and although the 2 isolates differed on PFGE analysis (Figure 1), the data strongly suggest that the infection of patient 2 was also transmitted zoonotically. The gene discussed is PRG4; the disease is infection.