FVC (1G/2G type, 1.7±0.1 L; 1G/1G type, 1.7±0.1 L, p<0.0001), and FEV1 (1G/2G type, 1.3±0.1 L; 1G/1G type, 1.2±0.1 L, p = 0.005) was significantly lower in bronchiectasis patients with at least one -1607G of MMP-1 polymorphism compared to those with 2G/2G genotype (FVC, 2.3±0.1 L; FEV1, 1.7±0.1 L) (Table 3). Here, MMP1 is linked to bronchiectasis.