CD4 and chronic kidney disease: Specific HIV-related factor independently associated with a higher risk of CKD in our study were, as reported by other reports, history of AIDS [14], [23] and a low current CD4 count [11], [14] The specific nephrotoxicity of AIDS-defining diseases treatments or prophylaxis (such as the use of trimethoprime-sulfamethoxazole) could not be assessed by lack of reliable data.