SSB and Sjogren syndrome: Central nervous system manifestations of a number of rheumatologic diseases, particularly Sjogren’s Syndrome, can mimic multiple sclerosis (MS).[1]–[2] As a consequence, serum autoantibodies, such as ANA, SSA, SSB, rheumatoid factor, anticardiolipin antibodies, and lupus anticoagulant, are frequently included in the diagnostic workup of patients suspected of having MS.